Using Command line API behaves differently

If I use this
“C:\Program Files (x86)\Google\Chrome\Application\chrome.exe” "file:///C:/
Xclick select different images.

If I use Play macro Xclick works fine.

What happends???

Could it be a timing issues? As test, please add a PAUSE | 5000 before the XClick, does it work then?

Also, make sure that the browser is in the foreground and not covered by any other app (including the UI Vision IDE). => Use BringBrowserToForeground