My big problem to use Waterfox are 2:
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I use more webextension that i combine with macros and if these extension are not available for Waterfox i can not work (some extension have no alternatives).
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Waterfox support only windows 7 with 64 bit, for me this is a big problem because i need to use browser at 32 bit for virtual box (not available at 64 bit).
random-agent-spoofer is now abandoned and is no longer updated so it is unusable today because it contains settings 2-3 years old, for this was born chanmeleon that every week is updated with the new settings of mobile browsers and I have not found any good alternative.